Thanksgiving Day NFL schedule 2022: Which teams are playing, kickoff times and more

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'Fox & Friends Weekend' hosts highlight the importance of family dinners, share favorite Thanksgiving sides

Founders of Tessemae Salad Dressing — Brian, Greg and Matt Vetter — join 'Fox & Friends Weekend' to discuss their salad dressing and talk about the importance of family dinners.

Thanksgiving Day football just hits different, and this season’s slate of action will feature three games with six teams vying for the playoffs.

The Buffalo Bills and the Detroit Lions start things off in the early afternoon as the appetizer for the day. The Dallas Cowboys and New York Giants will face off for the main course. 

And, for dessert, the Minnesota Vikings will take on the New England Patriots.

The Lions and the Cowboys are Thanksgiving Day staples like turkey, stuffing, mashed potatoes and awkward dinner table conversations. Detroit has hosted a Thanksgiving Day game every year since 1934, and Dallas has hosted a game every holiday since 1966 except for 1975 and 1977.

Minnesota Vikings cornerback Patrick Peterson (7) breaks up a pass intended for Arizona Cardinals wide receiver Robbie Anderson (81) during the second half of a game Oct. 30, 2022, in Minneapolis. (AP Photo/Abbie Parr)

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In 1925, the Chicago Bears and Chicago Cardinals played to a 0-0 tie at Wrigley Field in front of a crowd of 36,000. In 1934, the Lions played the Bears Thanksgiving Day in the first nationally televised broadcast of a football game. Bronko Nagurski threw a 2-yard touchdown pass to Bill Hewitt to seal a 19-16 victory in their first meeting.

This year, the NFL will honor the late John Madden throughout the day. Madden died at the age of 85 last year, just a few days after his documentary was released. The league said the inaugural "John Madden Thanksgiving Celebration" will feature special tributes on CBS, FOX and NBC throughout the slate of games.

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Lions (4-6) vs. Bills (7-3) – 12:30 p.m. ET, CBS

Detroit Lions running back Jamaal Williams (30) celebrates after scoring a touchdown during the first half of a game against the New York Giants Nov. 20, 2022, in East Rutherford, N.J.  (AP Photo/John Munson)

The Lions are in the mix on Thanksgiving as they are every year, and they are entering a matchup with the Bills looking to disrupt Buffalo’s playoff hopes. Detroit has won three straight behind Jared Goff, Jamaal Williams and an energized defense.

Buffalo got back in the saddle with a win over the Browns last week. Josh Allen hopes to curtail the mistakes against the Lions and not sink Buffalo in such a pivotal matchup at this point of the season. Allen is also undefeated on Thanksgiving (2-0). He had 204 passing yards and a touchdown pass in his previous Thanksgiving game against the Lions

Detroit will hope Jamaal Williams can continue his tear. He had three rushing touchdowns last week and became the fourth player since 2000 with multiple rushing touchdowns in at least five of his team’s first 10 games of a season.

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The Bills are 5-4-1 all-time on Thanksgiving, and the Lions are 37-43-2.

Cowboys (7-3) vs. Giants (7-3) – 4:30 p.m. ET, FOX

Donovan Wilson of the Dallas Cowboys takes down Daniel Jones (8) of the New York Giants at MetLife Stadium Sept. 26, 2022, in East Rutherford, N.J. The Cowboys defeated the Giants 23-16. (Jim McIsaac/Getty Images)

The Cowboys and Giants meet on Thanksgiving for the first time since 1992. The teams are in completely different spots than when they first met at MetLife Stadium Sept. 26.

Dallas is gaining momentum in its bid for an NFC East title. The Cowboys are seventh in points scored and 14th in yards gained, and their defense is first in points allowed and ninth in yards allowed. The Cowboys have won 10 out of their last 11 games against the Giants.

New York is looking to bounce back from a defeat at home to the Lions. But getting past the Dallas defense with an injury-riddled team is going to be a tough task. Especially when a guy like Micah Parsons is entering Reggie White territory.

Parsons recorded his eighth career game with at least two sacks, tying Shawne Merriman and Reggie White for the "second-most such games by a player in his first two NFL seasons since 1982," according to the NFL.

The Cowboys are 31-22-1 on Thanksgiving. The Giants are 6-4-3.

Vikings (8-2) vs. Patriots (6-4) – 8:20 p.m. ET, NBC

New England Patriots cornerback Marcus Jones (25) runs in a punt return for a touchdown during the second half of a game Nov. 20, 2022, in Foxborough, Mass. (AP Photo/Michael Dwyer)

Closing out the Thanksgiving festivities will be the Vikings and the Patriots.

New England is coming off an electric win over the New York Jets Sunday, thanks to a punt return touchdown from Marcus Jones. The Patriots have one of the best defenses in the league. That Pats are second in points allowed and fourth in yards allowed. It may be tough for the Vikings to get its offense going.

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But, of course, they have Justin Jefferson. The star wide receiver enters the game with 4,109 career receiving yards and could pass Randy Moss for the most receiving yards by a player in his first three seasons in NFL history.

Minnesota is 6-2 on Thanksgiving, and the Patriots are 3-2.