Obesity has been a known risk factor for a wide range of diseases for a very long time. Now, a new study published in the Journal of the American Heart Association has highlighted its link to heart-related deaths.

Across a 20-year span, the number of obesity-related heart disease deaths tripled in the U.S., researchers found.

Heart deaths were highest among Black people — particularly Black women — followed by individuals of American Indian or Alaska Native descent.

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"The number of people with obesity is rising in every country across the world," said cardiologist Zahra Raisi-Estabragh, M.D., a clinical lecturer at the William Harvey Research Institute in London, in a press release from the American Heart Association (AHA).

"Our study is the first to demonstrate that this increasing burden of obesity is translating into rising heart disease deaths," added Raisi-Estabragh, who was also the lead author of the study. 

Obese man with doctor

A new study published in the Journal of the American Heart Association highlights the link between obesity and heart-related deaths. (iStock)

"This rising trend of obesity is affecting some populations more than others, particularly Black women."

In the study, researchers analyzed electronic health records from 281,135 heart disease deaths in which obesity was noted as a "contributing factor" across the U.S. 

Then they looked at gender, race and setting (urban versus rural).

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Deaths from heart disease rose from 2.2 per 100,000 people to 6.6 per 100,000 people between 1999 and 2020, per the release.

Black women had the highest rates of fatal heart disease linked to obesity. For other racial groups, men were more likely to be affected than women. 

Black woman with doctor

Black women had the highest rates of fatal heart disease linked to obesity, researchers of a new study found. (iStock)

Black adults living in urban areas experienced more obesity-linked heart disease deaths compared to their counterparts in rural environments, the researchers also found.

The opposite was true for all other racial groups — with those living in rural areas at a higher risk.

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"The trend of higher obesity-related cardiovascular death rates for Black women than men was striking and different from all other racial groups considered in our study," said senior author Mamas A. Mamas, M.D., professor of cardiovascular medicine at Keele University in Keele, United Kingdom, in the AHA’s news release.

There are many reasons that obesity increases heart death risk, according to Dr. Marc Siegel, a professor of medicine at NYU Langone Medical Center and a Fox News medical contributor.

Cardiologist with patient

Cardiovascular disease is the leading cause of death in the United States, claiming 928,741 deaths in 2020, the AHA reported. (iStock)

One contributing factor is that inflammatory chemicals build up in white fat, he said, leading directly to increased clotting risks and buildup of coronary plaques, which can lead to sudden heart attacks. 

("White adipose tissue," or WAT, is a type of fat that stores energy in large fat droplets. An excess of this type of fat can raise the risk of developing obesity, heart disease, diabetes and other conditions, according to experts.)

"The number of people with obesity is rising in every country across the world."

"Obesity is also associated with a sedentary lifestyle, poor food choices that can cause high cholesterol, and high blood pressure — all of which also present direct increased risk of death from heart disease," said Siegel, who was not involved in the heart death study.

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Obesity also directly increases the risk of type 2 diabetes, the doctor added.

"This is because there are only so many insulin receptors per body surface area, which also increases the risk of heart disease and death from heart disease."

Heart doctor with patient

Over a 20-year span, the number of obesity-related heart disease deaths has tripled in the U.S., researchers found. (iStock)

The researchers indicated potential limitations of the study, including the possibility of errors in medical coding and data entry.

Approximately 42% of the U.S. population now has obesity, a 10% spike from the previous decade, according to data from the AHA.

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Cardiovascular disease is the leading cause of death in the United States, claiming 928,741 deaths in 2020, the AHA reported.

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Fox News Digital reached out to the lead study author for additional comment.